EXAMINATION OF COLORECTAL PSM CANCER WITH A SUBMUCOSAL INVASION DEPTH OF LESS THAN 1,000 μM

  • OONO Yasuhiro
    Department of Gastroenterology & GI Oncology, National Cancer Center Hospital East. Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center.
  • NAKAMURA Hisashi
    Department of Gastroenterology, Chofu Surgical Clinic.
  • IRIGUCHI Yosuke
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center.
  • YAMAMURA Akihiko
    Department of Pathology, Tokyo Metropolitan Cancer Detection Center.
  • OHURA Michihisa
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center.
  • IKEMATSU Hiroaki
    Department of Gastroenterology & GI Oncology, National Cancer Center Hospital East.
  • ODA Johji
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center.
  • MIZUTANI Masaru
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center.
  • TAKAYANAGI Satoshi
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center.
  • KISHI Daisuke
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center.
  • TOMINO Yasuhiro
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center.
  • FUJISAKI Tadashi
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center.
  • HOSOI Tozo
    Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center.

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Other Title
  • SM浸潤距離1,000μm未満の大腸pSM癌の検討

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Description

Based on the "Treatment Guidelines for Colorectal Cancer 2005 Edition", a new criterion for curative endoscopic treatment of submucosal cancer is "the submucosal invasion depth of the lesion is less than 1,000 μm". This study was designed to clarify the feature of the adaptation lesions, to examine the clinicopathological factor according to tumor distance, and the presence of vascular invasion (ly or v) by the submucosal invasion depth. As a result, (1) Lesions larger than 20 mm in diameter had a low EMR resection rate ; (2) As to the lesions with submucosal invasion of 300 to 1,000 μm, there was a high positive ratio of vascular invasion (28.9%). From this result, based on the new criterion for endoscopic treatment, it is important that the lump resection rate of lesions larger than 20 mm in diameter should be improved by endoscopic treatment, and the excision specimen is handled carefully to ensure an accurate histopathological diagnosis.

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