Shape changes of GSH-treated erythrocytes during complement-induced hemolysis.
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- MATSUMOTO NOBORU
- College of Medical Technology Yamaguchi University
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- HIROSHIGE YUKIO
- the Third Department of Internal Medicine, Yamaguchi University
Bibliographic Information
- Other Title
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- Shape Changes of GSH Treated Erythrocyt
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Description
Shape changes of GSH-treated human erythrocytes during the acidified serum test were examined by a differential interference microscope. A time-course study of the erythrocytes undergoing complement-mediated hemolysis revealed two kinds of hemolytic processes. One is rapid hemolysis, in which GSH-treated erythrocytes are transformed into spherical forms prior to hemolysis. The other process is gradual or slow hemolysis of a small proportion of GSH-treated erythrocytes. In this process, the erythrocytes are transformed into echinocytes and then into spheroechinocytes prior to hemolysis. However, echinocytic shape changes are not an absolute prerequisite to hemolysis, since echinocytes are not always transformed into a prelytic spherical form, but some of them are reversed to discocytes. Under the experimental conditions of this study, rapid hemolysis of spherical erythrocytes is the main mechanism of hemolysis.
Journal
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 132 (2), 199-205, 1980
Tohoku University Medical Press
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Details 詳細情報について
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- CRID
- 1390001204239332352
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- NII Article ID
- 130003407712
- 40005306676
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- NII Book ID
- AA00863920
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- COI
- 1:CAS:528:DyaL3MXivVOntw%3D%3D
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- ISSN
- 13493329
- 00408727
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- NDL BIB ID
- 2225878
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- PubMed
- 7444943
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed