A case of thrombasthenia with a study of platelet aggregation by hydrogen peroxide(H2O2)

DOI Web Site Web Site PubMed オープンアクセス

書誌事項

タイトル別名
  • A Case of Thrombasthenia with a Study of Platelet Aggregation by Hydrogen Peroxide (H<sub>2</sub>O<sub>2</sub>)

この論文をさがす

説明

A six-year-old girl with a congenital hemorrhagic disorder characteristic of thrombasthenia or Glanzmann's disease was reported. A special study on platelet aggregation was performed. It was found that patient's platelets failed to aggregate in response to hydrogen peroxide (H2O2), while normal platelets were readily aggregated by this agent. This H2O2 induced aggregation of normal platelets can be inhibited by adenosine, suggesting a possible mechanism that H2O2 might stimulate platelets to release ADP, which in turn causes platelet aggregation.

収録刊行物

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ