Incorporation of 14C-leucine into brain protein in rats with hyperaminoacidemia
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- TAKADA GORO
- Department of Pediatrics, Tohoku University School of Medicinei
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- TADA KEIYA
- Department of Pediatrics, Tohoku University School of Medicinei
書誌事項
- タイトル別名
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- Incorporation of <sup>14</sup>C-Leucine into Brain Protein in Rats with Hyperaminoacidemia
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抄録
In in vivo experiments on rats with experimentally induced hyperaminoacidemia, it was observed that when the plasma concentration of a single amino acid, such as phenylalanine, methionine, histidine or valine was elevated, both the uptake of 14C-leucine by the brain and the incorporation of 14C-leucine into the brain protein were inhibited. These findings suggest that the reduction of brain protein synthesis due to an imbalance of amino acid concentrations in serum may play an important role in the development of the brain damage seen in inbor, errors of amino acid metabolism.
収録刊行物
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 102 (2), 103-111, 1970
東北ジャーナル刊行会
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詳細情報 詳細情報について
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- CRID
- 1390001204240284416
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- NII論文ID
- 130003491478
- 40018682263
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- NII書誌ID
- AA00863920
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- COI
- 1:CAS:528:DyaE3MXosFGmtw%3D%3D
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- ISSN
- 13493329
- 00408727
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- NDL書誌ID
- 8507303
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- PubMed
- 5491780
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可