Reinnervation of the Denervated Muscle by Direct Nerve Implantation in Cats

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Abstract

The authors studied restoration of the function of denervated muscle in cats by implanting the proximal cut end of the peripheral nerve directly into acutely denervated muscle as well as into the muscle which had been denervated 10 weeks or 6 months previously. From the electromyographical, histological and histochemical studies on the muscle with nerve implanted, it was revealed that the chronically denervated muscle retained still an ability to recover its motor and stretch sensory functions. This suggests that this technique may be applicable to the peripheral nerve surgery in certain clinical cases.

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