Biosynthesis of Glycoproteins in the Stroma of Rat Adipose Tissue

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  • SATO TOKUTARO
    The Second Department of Internal Medicine, Tohoku University School of Medicine
  • OKUYAMA MAKIO
    The Second Department of Internal Medicine, Tohoku University School of Medicine
  • TORIKAI TATSUO
    The Second Department of Internal Medicine, Tohoku University School of Medicine

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Biosynthesis of glycoproteins in the connective tissue of the rat epididymal fat pads was studied in vitro. After incubation of the adipose tissue with glucose-1-14C, the carbohydrate containing polymers such as glycogen, several glycoproteins and acid mueopolysaccharides were extracted by the procedure of Robert et al. It was shown that glucose-1-14C was incorporated into glycoproteins in the stroma and into glycogen in the cells of the adipose tissue. However, no radioactivity was detected in acid mucopolysaccharides under the present experimental conditions.

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