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- MOTOKI RYOICHI
- The First Department of Surgery, Fukushima Medical School
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- HONDA KENJI
- The First Department of Surgery, Fukushima Medical School
Bibliographic Information
- Other Title
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- Hemodynamics in Sepsis Its Relationship
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Abstract
Serial clinical observations and hemodynamic measurements were made on seventeen patients with sepsis and ten control cases. Control patients were slightly hypovolemic immediately after operation. In the eleven high flow patients, that is, those with the initial cardiac index higher than 3.0 liters/min/m2, we observed characteristic hemodynamics with lowered vascular resistance, higher cardiac output and hypotension. The anomalous vascular resistance began to return to normal approximately 48 hr after operation. In three cases pulmonary complication developed at this time and therefore pulmonary artery pressure and/or pulmonary wedge pressure exceeded the normal range. In these cases treatment was aimed at lowering the pulmonary pressure. Pulmonary complication was improved when these pressures returned within normal range. In the seven low flow patients, that is, those with cardiac index lower than 2.9 liters/min/m2, we observed decreased cardiac index with increased systemic and pulmonary vascular resistance. In these cases pulmonary complication appeared to develop by increased permeability of the pulmonary capillary wall. Elevated pulmonary artery pressure might accelerate the progress of the complication. Monitoring and controlling pulmonary artery pressure and pulmonary wedge pressure were effective in prevention and treatment of pulmonary complication in this group.
Journal
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 123 (2), 109-124, 1977
Tohoku University Medical Press
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Details 詳細情報について
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- CRID
- 1390001204241262208
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- NII Article ID
- 130003492365
- 40005305997
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- NII Book ID
- AA00863920
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- COI
- 1:STN:280:DyaE1c%2FlsFGmtA%3D%3D
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- ISSN
- 13493329
- 00408727
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- NDL BIB ID
- 1913629
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- PubMed
- 929584
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed