Tissue Respiration of the Partially Denervated Dog Prostate

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The sacral nerves or the hypogastric nerve were divided in 23 adult male dogs, and QO2, QCO2 and the activities of succinic dehydrogenase (SDH) and latic de-hydrogenase (LDH) of the prostatic tissue were measured on the 7th and 21st postoperative days. The results were summarized as follows:<br> 1) QO2, QCO2 and R. Q. usually decreased after the interruption of prostatic innervation.<br> 2) Both SDH and LDH activities usually increased, while the SDH/LDH ratio was always reduced because the increase in LDH activity was larger than that of SDH.<br> 3) These changes were also observed after division of the hypogastric as well as the sacral nerves.<br> 4) The changes persisted for a considerably long period.

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