Clinical Application of the Fluorescent Antibody Technic to Dermatomycoses

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  • Miura Takashi
    Department of Dermatology Tohoku University School of Medicine

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The indirect fluorescent antibody technic was applied clinically to detection of an antibody or antibodies in the sera of patients with or without dermatophyte infection. By this technic the antibody or antibodies could be found at a high rate in the sera of patients with dermatophyte infection. But strong cross-reactions were observed between the sera and non-causative fungi, and no direct relationship was found between the intensity of the reaction and that of the infection. Clinical application of the method, therefore, is still open to research. Such antibodies were also found in the sera of not a few patients without the infection, but they could not be found in the sera of all the examined children. Subclinical but anti-body-stimulating infection of dermatophytes may be considered to play a role in the antibody formation.

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