A case of early-stage lung cancer detected by autofluorescence bronchoscopy

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  • Hanibuchi Masaki
    Department of Internal Medicine and Molecular Therapeutics, Course of Bioregulation and Medical Oncology, The University of Tokushima School of Medicine
  • Yano Seiji
    Department of Internal Medicine and Molecular Therapeutics, Course of Bioregulation and Medical Oncology, The University of Tokushima School of Medicine
  • Edakuni Nobutaka
    Department of Internal Medicine and Molecular Therapeutics, Course of Bioregulation and Medical Oncology, The University of Tokushima School of Medicine
  • Inayama Mami
    Department of Internal Medicine and Molecular Therapeutics, Course of Bioregulation and Medical Oncology, The University of Tokushima School of Medicine
  • Sone Saburo
    Department of Internal Medicine and Molecular Therapeutics, Course of Bioregulation and Medical Oncology, The University of Tokushima School of Medicine

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A 71-year-old man was referred to our hospital for further examination of abnormal sputum cytology. No abnormal nodular shadows were detected in chest X-ray and chest CT. The location of the tumor was clearly identified as a defect of autofluorescence by autofluorescence bronchoscopy at the bifurcation between the left B1+2 and B3 bronchi, whereas it was quite difficult by conventional bronchoscopy. Transbronchial biopsy revealed squamous cell carcinoma. Further examinations yielded the diagnosis of early-stage lung cancer. Photodynamic therapy was performed and complete response was confirmed. This case indicates the efficacy of autofluorescence bronchoscopy for detecting early-stage lung cancer.

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