An Electrochemical Biosensor for Nitric Oxide Based on Silver Nanoparticles and Hemoglobin
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- GAN Xin
- Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University
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- LIU Tao
- Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University
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- ZHU Xiaoli
- Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University
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- LI Genxi
- Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University
Bibliographic Information
- Other Title
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- Electrochemical Biosensor for Nitric Oxide Based on Silver Nanoparticles and Hemoglobin
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Abstract
A nitric oxide (NO) biosensor based on silver nanoparticles was fabricated with high sensitivity and selectivity as well as stability. Silver nanoparticles could preserve the microstructures of hemoglobin, but the electrochemical reactivity of the protein and its detection sensitivity toward NO could be greatly enhanced. Accordingly, a NO biosensor was developed. The linear concentration range was from 1.0 × 10-6 to 5.0 × 10-5 M. Its detection limit was 3.0 × 10-7 M with a sensitivity of 0.0424 µA µM-1 NO. The possible co-existing compounds would not interfere with the detection.
Journal
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- Analytical Sciences
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Analytical Sciences 20 (9), 1271-1275, 2004
The Japan Society for Analytical Chemistry
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Details 詳細情報について
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- CRID
- 1390001204255453696
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- NII Article ID
- 130004440985
- 10013524370
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- NII Book ID
- AA10500785
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- COI
- 1:CAS:528:DC%2BD2cXnvVGru7k%3D
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- ISSN
- 13482246
- 09106340
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- NDL BIB ID
- 7078605
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- PubMed
- 15478335
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- Web Site
- http://id.ndl.go.jp/bib/7078605
- https://ndlsearch.ndl.go.jp/books/R000000004-I7078605
- https://link.springer.com/content/pdf/10.2116/analsci.20.1271.pdf
- https://link.springer.com/article/10.2116/analsci.20.1271/fulltext.html
- http://www.jstage.jst.go.jp/article/analsci/20/9/20_9_1271/_pdf
- https://search.jamas.or.jp/link/ui/2006059914
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed