Sulfadiazine-Potentiometric Sensors for Flow and Batch Determinations of Sulfadiazine in Drugs and Biological Fluids

DOI HANDLE PDF Web Site Web Site ほか1件をすべて表示 一部だけ表示 被引用文献1件 参考文献41件 オープンアクセス

この論文をさがす

説明

New PVC membrane electrodes for the determination of sulfadiazine (SDZ) are presented. The electrodes are fabricated with conventional and tubular configurations with a graphite-based electrical contact, and no internal reference solution. The selective membranes consist of bis(triphenylphosphoranilidene)ammonium·SDZ (electrode A), tetraoctylammonium bromide (electrode B), or iron(II)-phthalocyanine (FePC) (electrode C) electroactive materials dispersed in a PVC matrix of o-nitrophenyl octyl ether (o-NPOE) plasticizer. The sensors A, B, and C displayed linear responses over the concentration ranges 1.0 × 10-2 - 1.0 × 10-5, 1.0 × 10-2 - 7.5 × 10-6, and 3.2 × 10-2 - 7.0 × 10-6 mol l-1 (detection limits of 1.09, 2.04 and 0.87 µg ml-1) with anionic slopes of -57.3 ± 0.1, -46.7 ± 0.5, and -65.1 ± 0.2 mV decade-1, respectively. No effect from pH was observed within 4.0 - 5.5, 4.8 - 10, and 4.5 - 8, respectively, and good selectivity was found. The sensors were applied to the analysis of pharmaceuticals and biological fluids in steady state and in flow conditions.

収録刊行物

  • Analytical Sciences

    Analytical Sciences 25 (3), 365-371, 2009

    社団法人 日本分析化学会

被引用文献 (1)*注記

もっと見る

参考文献 (41)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ