Glucose Sensor Based on Glucose Oxidase Immobilized by Zirconium Phosphate

DOI PDF Web Site Web Site Web Site ほか1件をすべて表示 一部だけ表示 被引用文献1件 参考文献31件
  • PARK Sejin
    Department of Chemistry, Sungshin Women’s University Department of Biomedical Engineering, College of Medicine and Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University
  • CHUNG Taek Dong
    Department of Chemistry, Sungshin Women’s University
  • KANG Sun Kil
    Department of Biomedical Engineering, College of Medicine and Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University
  • JEONG Ran-A
    Department of Chemistry, Sungshin Women’s University Department of Biomedical Engineering, College of Medicine and Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University
  • BOO Hankil
    Department of Chemistry, Sungshin Women’s University Department of Biomedical Engineering, College of Medicine and Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University
  • KIM Hee Chan
    Department of Biomedical Engineering, College of Medicine and Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University

この論文をさがす

抄録

Amperometric glucose sensors were fabricated using glucose oxidase (GOx) entrapped in zirconium hydrogenphosphate (ZrP), and their performance was evaluated. Reportedly, α-ZrP is one of the candidates that are expected to improve the stability of enzymes immobilized on solid surfaces.1,2 We intercalated GOxs into ZrP (GOx/ZrP), cast the GOx/ZrP suspension in polyvinylalcohol on a platinum electrode, and dried it in a vacuum oven. The morphological layered structure was investigated by scanning electron microscopy. The enzymatic activities, which were determined by open-circuit potentiometric technique, reached the highest when GOxs were immobilized in ZrP at ca. pH 5. In vitro tests showed good linear responses in the 0 - 25 mM range and the sensitivity of 0.14 nA mM-1 at 0.4 V vs. Ag/AgCl. The sensors, as made, were stable for more than 3 days within a limited deterioration.

収録刊行物

  • Analytical Sciences

    Analytical Sciences 20 (12), 1635-1638, 2004

    社団法人 日本分析化学会

被引用文献 (1)*注記

もっと見る

参考文献 (31)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ