Rapid and Sensitive Detection of Vinorelbine in the Urine of Tumor Patients by Capillary Electrophoresis with Tris(2,2'-bipyridyl)ruthenium(Ⅱ)-based Electrochemiluminescence Assay

DOI PDF Web Site Web Site Web Site ほか1件をすべて表示 一部だけ表示 参考文献47件
  • ZHOU Qing-Wei
    Department of Biochemistry and Molecular Biology, Institute of Frontier Medical Sciences, Jilin University
  • WU Di
    Tumorology Department of Jilin Province Tumor Hospital
  • MENG Qin
    Chemistry Laboratory for Traditional Chinese Medicine, Pharmaceutical College, Jilin University
  • TANG Hai-Bo
    Tumorology Department of Jilin Province Tumor Hospital
  • WEI Zheng-Ren
    Chemistry Laboratory for Traditional Chinese Medicine, Pharmaceutical College, Jilin University
  • KUANG Ye
    Chemistry Laboratory for Traditional Chinese Medicine, Pharmaceutical College, Jilin University
  • YIN Jian-Yuan
    Chemistry Laboratory for Traditional Chinese Medicine, Pharmaceutical College, Jilin University
  • CHEN Jia-Jun
    Neurology Departmemt of China-Japan Union Hospital, Jilin University

書誌事項

タイトル別名
  • Rapid and Sensitive Detection of Vinorelbine in the Urine of Tumor Patients by Capillary Electrophoresis with Tris(2,2′-bipyridyl)ruthenium(II)-based Electrochemiluminescence Assay

この論文をさがす

抄録

A capillary electrophoresis method coupled with electrochemiluminescence detection for the analysis of vinorelbine (VNB) in the urine of tumor patients was established in this research. Complete determination of VNB was achieved in 8 min using a background electrolyte of 50 mmol/L phosphate buffer (pH 9.0) and a separation voltage of 15 kV. The calibration curves showed a linear range from 2.8 × 10−10 to 1.6 × 10−8 mol/L. The relative standard derivation for VNB was below 3.4%. The linear relationships were good and the correlation factor of VNB exceeded 0.985. The detection limits were 1.0 × 10−11 mol/L under the optimal conditions. The developed method was applied to the sensitive determination of VNB in the urine of tumor patients.

収録刊行物

  • Analytical Sciences

    Analytical Sciences 29 (7), 757-760, 2013

    社団法人 日本分析化学会

参考文献 (47)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ