A Facile Preparation of Glass-supported Lipid Bilayers for Analyzing Molecular Dynamics

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  • ITO Yuma
    Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology Center for Integrative Medical Sciences, RIKEN
  • SAKATA-SOGAWA Kumiko
    Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology Center for Integrative Medical Sciences, RIKEN
  • TOKUNAGA Makio
    Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology Center for Integrative Medical Sciences, RIKEN

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説明

Many research programs focus on the molecular dynamics of living cells. This research requires cells to be adhered to a substrate while retaining the innate motility of their surface molecules. Lipid bilayer-based systems fulfill this requirement, although current methods are complicated and their utility is limited. We developed a simple and rapid method for reproducible preparation of homogeneous glass-supported lipid bilayers. Our method provides a facile means for bioimaging and analysis of molecular dynamics in living cells.

収録刊行物

  • Analytical Sciences

    Analytical Sciences 30 (12), 1103-1106, 2014

    社団法人 日本分析化学会

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