Roxithromycin Treatment of Chronic Sinusitis. A Clinical Evaluation.

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  • 慢性副鼻腔炎に対するルリッドの効果
  • マンセイ フクビクウエン ニ タイスル ルリッド ノ コウカ

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Abstract

The clinical efficacy of roxithromycin was examined objectively in 17 patients with chronic sinusitis. X-ray opacity of the maxillary sinuses and changes in subjective symptoms and objective signs were evaluated.<br>The patients were treated with 300mg of roxithromycin per day for 55.2 days on the average. X-ray opacity was evaluated with a microdensitometer, and the ratio of the maxillary sinus density to the orbital density (M/O ratio) was calculated.<br>Subjective improvement was noted in 70.6% and objective improvement in 58.8%. The M/O ratio was reduced in 42.1%, and clinical symptoms decreased in most of those with an improved M/O ratio. Nasal mucosal swelling was observed in 91.0% of the patients who didn't improve in M/O ratio after treatment. It was concluded that patients with mucosal swelling need surgical treatment.

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