A Fluorescence Probe Based on Biomolecule-stabilized Gold Nanoclusters for the Detection of Pazufloxacin Mesilate
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- CAO Xueling
- State Key Laboratory of Supramolecular Structure and Materials, Jilin University Department of Chemistry, Jilin Institute of Chemical Technology
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- LIAN Lili
- State Key Laboratory of Supramolecular Structure and Materials, Jilin University Department of Chemistry, Jilin Institute of Chemical Technology
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- LI Hongwei
- State Key Laboratory of Supramolecular Structure and Materials, Jilin University
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- WU Yuqing
- State Key Laboratory of Supramolecular Structure and Materials, Jilin University
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- LOU Dawei
- Department of Chemistry, Jilin Institute of Chemical Technology
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Abstract
In the present study, biomolecule-stabilized Au nanoclusters were demonstrated as a novel fluorescence probe for sensitive and selective detection of pazufloxacin mesilate (PZFX) for the first time. The linear decrease in the fluorescence intensity of Au nanoclusters induced by PZFX allowed for the quantitative detection of PZFX in the range of 0.15 μg/mL to 1 mg/mL, and the detection limit for PZFX was 0.2 μg/mL. Circular dichroism spectroscopy and fluorescence decay studies were then performed to discuss the quenching mechanism. In addition, practical application of the present approach was also demonstrated for real samples, which suggested its great potential for accurate analysis of similar drugs.
Journal
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- Analytical Sciences
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Analytical Sciences 30 (8), 817-822, 2014
The Japan Society for Analytical Chemistry
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Details 詳細情報について
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- CRID
- 1390001204259860096
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- NII Article ID
- 130004677857
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- NII Book ID
- AA10500785
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- COI
- 1:STN:280:DC%2BC2M%2Fgs1Ortw%3D%3D
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- ISSN
- 13482246
- 09106340
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- NDL BIB ID
- 025633252
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- PubMed
- 25109644
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- Web Site
- https://ndlsearch.ndl.go.jp/books/R000000004-I025633252
- https://link.springer.com/content/pdf/10.2116/analsci.30.817.pdf
- https://link.springer.com/article/10.2116/analsci.30.817/fulltext.html
- https://www.jstage.jst.go.jp/article/analsci/30/8/30_817/_pdf
- https://search.jamas.or.jp/link/ui/2015062394
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed