Label-free Detection of Antigen Protein Using a Metal Mesh Device Surface-modified by an Antibody
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- SETO Hirokazu
- Graduate School of Engineering, Kyushu University
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- KAMBA Seiji
- Murata Manufacturing Co.
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- KONDO Takashi
- Murata Manufacturing Co.
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- OGAWA Yuichi
- Graduate School of Agriculture, Kyoto University
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- HOSHINO Yu
- Graduate School of Engineering, Kyushu University
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- MIURA Yoshiko
- Graduate School of Engineering, Kyushu University
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Abstract
A biosensor for protein detection was developed using antibody-immobilized metal mesh devices. Antihemoglobin antibodies were covalently immobilized on a metal mesh device. Extraordinary transmission with a dipped structure was observed for a metal mesh device immobilized with antihemoglobin antibodies as well as for the original metal mesh device. Hemoglobin in the mixture solution containing albumin at a hundred-fold concentration was detectable using antihemoglobin-immobilized MMDs. The detectability using the antihemoglobin-immobilized metal mesh device was similar to that of a commercially-available kit for the qualitative determination of hemoglobin.
Journal
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- Analytical Sciences
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Analytical Sciences 31 (3), 173-176, 2015
The Japan Society for Analytical Chemistry
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Details 詳細情報について
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- CRID
- 1390001204260263552
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- NII Article ID
- 130004827468
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- NII Book ID
- AA10500785
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- ISSN
- 13482246
- 09106340
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- NDL BIB ID
- 026247302
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- PubMed
- 25765271
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- Web Site
- http://id.ndl.go.jp/bib/026247302
- https://ndlsearch.ndl.go.jp/books/R000000004-I026247302
- https://link.springer.com/content/pdf/10.2116/analsci.31.173.pdf
- https://link.springer.com/article/10.2116/analsci.31.173/fulltext.html
- https://www.jstage.jst.go.jp/article/analsci/31/3/31_173/_pdf
- https://search.jamas.or.jp/link/ui/2015280986
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed