Placement of Nanospace on an Electrode for Biosensing

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  • SHIIGI Hiroshi
    Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University
  • TOKONAMI Shiho
    Nanoscience and Nanotechnology Research Center, Osaka Prefecture University
  • YAMAMOTO Yojiro
    Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University GreenChem. Inc.
  • NAGAOKA Tsutomu
    Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University

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Description

Electrical and electrochemical methods are well established as very useful techniques in the field of biosensing because they can easily handle signals and devices. This paper provides an overview of biosensing using a nanometer-sized space functionally. Placed effectively on the electrode, the nanospace offers several advantages, such as increased sensitivity, improved selectivity, decreased response time, and the potential for instrument miniaturization. Given the impressive technological progress of nanospace biosensors and its growing impact on analytical science, this review offers an easy-to-understand presentation describing the history, recent advances, new methods, and future prospects of nanospace biosensors.

Journal

  • Analytical Sciences

    Analytical Sciences 28 (11), 1037-1048, 2012

    The Japan Society for Analytical Chemistry

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