Six Cases of Malignant Melanoma in the Head and Neck Region.

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  • 頭頚部粘膜に生じた悪性黒色腫６例

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Abstract

Six cases of malignant melanoma occurring in the head and neck region, and treated at National Defense Medical College from 1989 to 1997, are presented. Patient age ranged from 42 to 79 years and all cases were male.<br>The location of the tumor was the nasal mucosa in 3 patients, oral mucosa in 1 patient and laryngeal mucosa in 2 patients. The 2 cases of laryngeal tumor were considered to be metastatic. Histologically, three cases were diagnosed as amelanotic melanoma, 2 cases as melanotic melanoma and 1 case as amelanotic and melanotic melanoma. Two patients were treated with chemotherapy. One patient was treated with chemotherapy and immunotherapy. One patient was treated with surgery and immunotherapy. One patient was treated with surgery and chemotherapy. One patient was treated with surgery, radiation and immunotherapy. Five cases died of metastasis. Only one patient remains alive on having tumor as of June, 1997.

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