小児鼻副鼻腔炎に対するＥＭ少量投与法

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  • Efficacy of Low Dose Erythromycin Treatment of Sinusitis in Children.
  • ショウニ ビ フクビクウエン ニ タイスル EM ショウリョウ トウヨホウ

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The clinical efficacy of low dose erythromycin (10mg/kg/day) was investigated in 58 children with sinusitis.<br>1. Intranasal findings were completely cleared in 50.0% of patients, improved in 25.9% and unchanged in 24.1%. Follow-up X-ray films of the sinuses showed complete cure of the disease in 13.3%, improvement in 53.3% and no change in 33.3%.<br>2. The shorter the period of infection, the higher was the response rate.<br>3. Patients below 4 years of age showed a much better response to this treatment than did patients above 4 years of age.<br>4. Treatment for two months is recommended for maximum efficacy.<br>5. Mild diarrhea in one patient was the only side effect observed. In conclusion, our data indicate that low dose erythromycin is useful in the treatment of children with sinusitis.

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