Mechanisms on the Development of Tonsillar Focal Infections

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  • 扁桃病巣感染症の発症機序の解明―掌蹠膿疱症とＩｇＡ腎症を中心に―
  • ヘントウ ビョウソウ カンセンショウ ノ ハッショウ キジョ ノ カイメイ ショウセキノウホウショウ ト IgAジンショウ オ チュウシン ニ
  • 掌蹠膿疱症とIgA腎症を中心に

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Pustulosis palmaris et plantaris (PPP), Sterno-costo-claviclar hyperostosis (SCCH), IgA nephropathy, and some other autoimmune diseases have been regarded as tonsillar focal infections since tonsillectomy is quite effective in the treatment of these diseases. In this paper, we reviewed recent clinicopathological evidence on tonsillar focal infections obtained through our experience as well as in the literature. In addition, we summarized experimental results regarding mechanisms of the development and progression of tonsillar focal infections. It has been speculated that abnormal immune responses in the tonsils may cause or worsen the disease. Therefore, tonsillectomy should be recommended for the treatment of tonsillar focal infections.

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