A Case of Wegener's Granulomatosis as Unilateral Parotid Enlargement
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- Kanazawa Yuji
- Kobe City Medical Center General Hospital
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- Shinohara Shogo
- Kobe City Medical Center General Hospital
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- Fujiwara Keizo
- Kobe City Medical Center General Hospital
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- Kikuchi Masahiro
- Kobe City Medical Center General Hospital
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- Yamazaki Hiroshi
- Kobe City Medical Center General Hospital
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- Kurihara Risa
- Kobe City Medical Center General Hospital
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- Naito Yasushi
- Kobe City Medical Center General Hospital
Bibliographic Information
- Other Title
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- 耳下腺腫脹を呈したウェゲナー肉芽腫例
- 臨床 耳下腺腫脹を呈したウェゲナー肉芽腫例
- リンショウ ジカセン シュチョウ オ テイシタ ウェゲナー ニクゲシュレイ
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Abstract
A 65-year-old man admitted for a left parotid tumor and high fever unresponsive to peroral antibiotics was found in gallium scintigraphy to have “hot” spots in the left parotid gland and left maxillary sinus. The ineffectiveness of intravenous antibiotics necessitated open biopsy to histologically diagnose the man’s condition. Surgical parotid gland and maxillary sinus specimens showed necrotizing granulomas with giant cells. Elevated proteinase-3 antineutrophil cytoplasmic antibody (PR3-ANCA) comfirmed a clinical diagnosis of Wegener’s granulomatosis. Treatment with prednisolone and cyclophosphamide led to clinical improvement.<br> Major salivary gland involvement is rarely a presenting symptom in Wegener’s granulomatosis and correctly diagnosing this condition may increase morbidity due to disease progression.<br>
Journal
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- Practica Oto-Rhino-Laryngologica
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Practica Oto-Rhino-Laryngologica 104 (3), 193-197, 2011
The Society of Practical Otolaryngology
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Details 詳細情報について
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- CRID
- 1390001204263513216
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- NII Article ID
- 10027794147
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- NII Book ID
- AN00107089
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- ISSN
- 18844545
- 00326313
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- NDL BIB ID
- 11030341
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed