Effects of the Herbal Medicine "Juzen-taiho-to" on Otitis-Prone Children
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- Maruyama Yumiko
- Kurobe City Hospital
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- Hoshida Shigeru
- Kurobe City Hospital
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- Ito Makoto
- Kanazawa University Graduate School of Medicine
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- Furukawa Mitsuru
- Kanazawa University Graduate School of Medicine
Bibliographic Information
- Other Title
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- 小児反復性中耳炎に対する十全大補湯の効果
- ヤクブツ ショウニ ハンプクセイ チュウジエン ニ タイスル ジュウゼンタイホトウ ノ コウカ
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Abstract
Juzen-taiho-to (JTT) is known as a herbal medicine that improves immune function. We evaluated whether JTT has a beneficial effect in otitis-prone children. Twenty otitis-prone infants took JTT at 0.1-0.14mg/kg/day twice a day for three months. The medication compliance rate was 85%. The frequency of otitis media purulenta significantly decreased (t-test, p=.000, Wilcoxon signed rank test, p=.000) by the oral administration of JTT. The number of days of fever (t, p=.000, Wilcoxon, p=.000), antibiotic administration (t, p=.002, Wilcoxon, p=.001), hospital visits (t, p=.014, Wilcoxon, p=.005), and emergency hospital visits (t, p=.000, Wilcoxon, p=.000) also showed significant decreases after taking JTT as compared with before.<br>The onset and progression of infection depends on the balance between the reproductive power of microbes and host defense. The effects of JTT on otitis-prone individuals have not been investigated before. JTT is thought to be one of the effective treatments for otitis-prone cases, and avoiding the overuse of antibiotics would prevent the increase of drug-resistant bacteria both in terms of their number and level of resistance.
Journal
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- Practica Oto-Rhino-Laryngologica
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Practica Oto-Rhino-Laryngologica 100 (2), 127-135, 2007
The Society of Practical Otolaryngology
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Details 詳細情報について
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- CRID
- 1390001204265045120
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- NII Article ID
- 10018494852
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- NII Book ID
- AN00107089
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- ISSN
- 18844545
- 00326313
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- NDL BIB ID
- 8669565
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed