Studies on histamine containing cells in the spleen of the magnesium-deficient rats.
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- ISHIGURO Shigeru
- Department of Veterinary Pharmacology, Faculty of Agriculture, Kagoshima University
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- NISIO Akira
- Department of Veterinary Pharmacology, Faculty of Agriculture, Kagoshima University
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- MIYAO Noboru
- Department of Veterinary Pharmacology, Faculty of Agriculture, Kagoshima University
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- MORIKAWA Yoshio
- Department of Veterinary Anatomy, College of Agriculture, University of Osaka Prefecture
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- TAKENO Kazu
- Department of Veterinary Pharmacology, College of Agriculture, University of Osaka Prefecture
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- YANAGIYA Iwao
- Department of Veterinary Pharmacology, College of Agriculture, University of Osaka Prefecture
Bibliographic Information
- Other Title
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- マグネシウム欠乏ラットひ臓のヒスタミン含有細胞
- マグネシウム ケツボウ ラット ヒゾウ ノ ヒスタミン ガンユウ サイボウ
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Abstract
When young Wistar rats (body wt. 50 g) were maintained on a magnesium-deficient diet (0.001% Mg) for eight days, the splenic weight and histamine content increased about 2-fold and 30-fold, respectively, compared with those of the control rats. There was no significant difference in the number of splenic mast cells between the magnesium-deficient and control rats. More neutrophilic, eosinophilic and basophilic granular cells were found in the spleen cells isolated from the magnesium-deficient rats than in those from the control rats. Of the isolated cells from magnesium-deficient rats, 7.6% were basophilic granular cells; however, no basophilic granular cells were observed in the spleen cells isolated from the control rats. In the cytochemical study, the yellowish fluorochrome formed by the interaction of o-phthalaldehyde and histamine was found in basophilic granular cells. These results suggest that the increase in the histamine content of the spleen of magnesium-deficient rats is related to the increased number of basophilic granular cells.
Journal
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- Folia Pharmacologica Japonica
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Folia Pharmacologica Japonica 90 (3), 141-146, 1987
The Japanese Pharmacological Society
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Keywords
Details 詳細情報について
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- CRID
- 1390001204270757504
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- NII Article ID
- 130000759463
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- NII Book ID
- AN00198335
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- ISSN
- 13478397
- 00155691
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- NDL BIB ID
- 3147239
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- PubMed
- 3428772
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed