Atropine様薬物の抗Muscarine作用と神経節遮断作用との比較

書誌事項

タイトル別名
  • Comparison between the antimuscarinic and ganglion blocking activities of several atropine like drugs
  • Atropine ヨウ ヤクブツ ノ コウMuscarine サヨウ ト シンケイセツ シャダン サヨウ ト ノ ヒカク

この論文をさがす

説明

The antimuscarinic and ganglion blocking activitities were compared in dogs, cats and the isolated guinea-pig ileums.<BR> The inhibitory effect of each drug on the gastric spontaneous motility and the salivation induced by the stimulation of the chorda tympani coincided with that on the hypotension induced by the stimulation of the vagus nerve respectively, but not with the acetylcholine-induced hypotension. These antimuscarinic activities of drugs in dogs were quite different from these ganglion blocking activity in cats. The relationship between the protective and lytic activities of drugs against acetylcholine-induced contraction in the isolated guinea-pig ileum corresponded with that against the hypotension induced by the acetylcholine administration and the vagus stimulation.

収録刊行物

  • 日本薬理学雑誌

    日本薬理学雑誌 66 (6), 607-617, 1970

    公益社団法人 日本薬理学会

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ