諸種薬物によるスルホヘモグロビン形成に関する研究　ＩＩＩ

DOI Web Site PubMed

書誌事項

タイトル別名
  • Studies of sulfhemoglobin formation by various drugs (3).
  • ショシュ ヤクブツ ニヨル Sulfhemoglobin ケイセイ ニカンスル

この論文をさがす

抄録

Sulfhemoglobin (SHb) and methemoglobin (MHb) formations by various compounds were examined by single and three consecutive intraperitoneal administrations to mice. With a single administration, methemoglobinemia was induced by diphenylamine (DPA), 1-naphthylamine (NA), phenylnaphthylamine (PNA), N-(1-naphthyl) anthranilic acid (N1) and N-(1´-naphthyl)-2-aminophenylacetic acid (IG240), and was not observed with phenylanthranilic acid (PAA), N-benzoyl-N´-phenyl-2, 6-diaminobenzoic acid (BPAA), flufenamic acid (FA), mefenamic acid (MFA), N-(2, 6-dichlorophenyl) anthranilic acid (CPAA), N-(2´, 6´-dichlorophenyl)-2-aminophenylacetic acid (CPPA), nine derivatives of N1I and two derivatives of IG240. On the other hand, sulihemoglobinemia, with a single administration, was found to be induced by NA. Furthermore, with three consecutive administrations, such was induced by DPA, PAA, BPAA and FA even though SHb was not demonstrated with a single administration, and was not observed with MF, CPAA, CPPA and various derivatives of NI and IG240.

収録刊行物

  • 日本薬理学雑誌

    日本薬理学雑誌 73 (7), 793-802, 1977

    公益社団法人 日本薬理学会

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ