Methodology of chronic cardiovascular pharmacological study in the unanesthetized and unrestrained dog.

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  • NONAKA Kazuko
    Department of Pharmacology and Experimental Therapeutics, Nagasaki University School of Medicine
  • UENO Akira
    Department of Pharmacology and Experimental Therapeutics, Nagasaki University School of Medicine

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  • 無麻酔無拘束犬における循環器機能研究の方法論
  • ム マスイ ム コウソク イヌ ニ オケル ジュンカンキ キノウ ケンキュウ

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Description

We have described and criticized the methods, techniques and materials used in our laboratory to obtain arterial and venous pressures, arterial and venous blood flows, cardiac output, internal diameter and pressure of the left ventricle, ECG and vascular diameters in unanesthetized and unrestrained dogs using both radiotelemetering systems and a direct wire connecting system.

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