Mechanisms of psychotropics' action in relation to CNS neurogenesis
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- UJIHARA Hisamitsu
- Division of Psychiatry, Geisei Hospital
Bibliographic Information
- Other Title
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- 向精神薬の作用機序:神経細胞新生との関係
- コウ セイシンヤク ノ サヨウ キジョ シンケイ サイボウ シンセイ ト ノ カンケイ
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Abstract
Newly available psychotropics seem to put the practical psychiatry to a stage of reform. In addition, the recent advancements in the study of neurogenesis in the adult brain force the change of the therapeutic strategy of mental disorders. The fact that the central nervous tissues can repair even after the maturation and that the replacement of neurons continues during adulthood will alter our understanding about their pathogenesis. The action of several psychiatric medications such as antidepressants, mood stabilizers, antipsychotics, and electroconvulsive therapy is converging at neurogenesis and/or neuroprotection. When the validity of the “neurogenesis/neuroprotection hypothesis” of psychiatric medication will be proved in psychiatric practice, we can establish a more rational and more effective treatment of mental disorders.<br>
Journal
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- Folia Pharmacologica Japonica
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Folia Pharmacologica Japonica 123 (5), 319-328, 2004
The Japanese Pharmacological Society
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Details 詳細情報について
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- CRID
- 1390001204272179840
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- NII Article ID
- 10013601608
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- NII Book ID
- AN00198335
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- ISSN
- 13478397
- 00155691
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- NDL BIB ID
- 6940449
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- PubMed
- 15118256
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed