Diagnosis of Eosinophilic Sinusitis in a Private Clinic

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  • 診療所における好酸球性副鼻腔炎の診断
  • 臨床 診療所における好酸球性副鼻腔炎の診断
  • リンショウ シンリョウジョ ニ オケル コウサンキュウセイ フクビコウエン ノ シンダン

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Abstract

Despite the concept of eosinophilic sinusitis becoming accepted widely in recent years, the diagnostic criteria remain unclear and definitive diagnosis requires histological proof of eosinophilic infiltration. Since it is not feasible for private otolaryngologists to sample tissue from deep within the paranasal sinuses, we examined if there might be another useful methods to establish the diagnosis of eosinophilic sinusitis before commencing treatment. In 43 cases of sinusitis (17 cases of eosinophilic sinusitis and 26 cases of non-eosinophilic sinusitis) of adult-onset, bilateral multiple polyps, and smell disturbance, we found significantly increased numbers of circulating eosinophils, high E/M values, and a high incidence of a prominence of the ethmoidal sinus on plain X-rays. The sensitivity, specificity, and accuracy of a blood eosinophil count of greater than 462 and prominence of the ethmoidal sinus on a plain x-ray of the sinuses for the diagnosis of eosinophilic sinusitis were 69.2%, 100%, and 88.2%, respectively. On the basis of these results, we propose that private otolaryngologists can also diagnose eosinophilic sinusitis based on history and medical examination, blood tests, and plain radiographs of the sinuses.<br>

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