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- YANAGIHARA Yukiyoshi
- Clinical Research Center for Allergy, National Sagamihara Hospital
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- KODA Akihide
- Department of Pharmacology, Gifu Pharmaceutical University
Bibliographic Information
- Other Title
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- IgE抗体産生の調節に対する免疫薬理学的アプローチ
- IgE コウタイ サンセイ ノ チョウセツ ニ タイスル メンエキ ヤクリガク
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Abstract
Soluble factors released by both T and B cells are involved in the class-specific regulation of IgE antibody formation; some factors have affinity for IgE, whereas others do not. The induction phase of the primary and secondary IgE antibody response is highly sensitive to treatment with such factors or some drugs. In contrast, persistent IgE antibody formation is mostly insensitive to the same treatments, indicating that this phase differs apparently from the induction phase. Thus, it is very important to note the marked differences between the regulatory mechanisms of these two phases when drugs responsible for the suppression of IgE antibody response are developed. In the present review, the recent advances pertaining to the regulation of IgE antibody formation in animals and humans are described in view of immunopharmacology.
Journal
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- Folia Pharmacologica Japonica
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Folia Pharmacologica Japonica 90 (1), 1-11, 1987
The Japanese Pharmacological Society
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Keywords
Details 詳細情報について
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- CRID
- 1390001204273714816
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- NII Article ID
- 130000759448
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- NII Book ID
- AN00198335
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- DOI
- 10.1254/fpj.90.1
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- ISSN
- 13478397
- 00155691
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- NDL BIB ID
- 3136125
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- PubMed
- 3308659
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed