Toluene A1ters Mu-Opioid Receptor Expression in the Rat Brainstem
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- SARACIBAR Gonzalo
- Department of Physiology, School of Pharmacy, University of the Basque Country
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- HERNANDEZ Maria Luisa
- Department of Physiology, School of Pharmacy, University of the Basque Country
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- ECHEVARRIA Enrique
- Department of Physiology, School of Pharmacy, University of the Basque Country
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- BARBERO Ismael
- Department of Physiology, School of Pharmacy, University of the Basque Country
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- GUTIERREZ Arantza
- Department of Physiology, School of Pharmacy, University of the Basque Country
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- CASIS Oscar
- Department of Physiology, School of Pharmacy, University of the Basque Country
書誌事項
- タイトル別名
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- Toluene Alters Mu-Opioid Receptor Expression in the Rat Brainstem.
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抄録
Toluene is an ototoxic organic solvent widely used in industry and could be a cause of sleep apnea. Acute toluene administration in rats induces an increase in the number of neural cells immunostained for mu-opioid receptors in several brainstem nuclei, such as the inferior colliculus, dorsal and lateral periaqueductal gray and dorsal raphe, without changes in the superior colliculus and the interpeduncular and lateral reticular nuclei. These data suggest that mu-opioid receptors could be involved in toluene-induced neurotoxic effects on the physiological regulation of breathing during sleep, and auditive function.
収録刊行物
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- Industrial health
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Industrial health 39 (3), 231-234, 2001
独立行政法人 労働者健康安全機構 労働安全衛生総合研究所
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詳細情報 詳細情報について
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- CRID
- 1390001204279532800
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- NII論文ID
- 130003551004
- 40005265743
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- NII書誌ID
- AA00672955
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- COI
- 1:CAS:528:DC%2BD3MXmtFKqtLk%3D
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- ISSN
- 18808026
- 00198366
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- NDL書誌ID
- 5995489
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- PubMed
- 11499998
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可