-
- CHIBA Shigetoshi
- Department of Pharmacology, Tohoku University School of Medicine
-
- HASHIMOTO Koroku
- Department of Pharmacology, Tohoku University School of Medicine
書誌事項
- タイトル別名
-
- SUSTAINED ATRIAL FIBRILLATION INDUCED BY CARBACHOL, METHACHOLINE AND BETHANECHOL
この論文をさがす
抄録
In 1955, Burn et al. (1) succeeded in the maintenance of atrial fibrillation by continuous infusion of acetylcholine (ACh) in the dog heart-lung preparation when atrial fibrillation was induced by electric stimulation of auricle. Recently, Hashimoto et al. (2) arranged an adequate method for the selective use of drugs into the sinus node artery in situ by modifying the original preparation developed by James and Nadeau (3), Hashimoto et al. (4) observed that atrial fibrillation was regularly induced by the administration of ACh into the sinus node artery under constant pressure perfusion. They analyzed the mechanism for induction of atrial arrhythmia with ACh, assuming the necessary participation of adrenergic mechanism with essential cholinergic effect of ACh. More recently, Nakayama et al. (5) obtained sustaining atrial fibrillation by continuous infusion of a relatively small amount of ACh directly into the sinus node artery.<BR> In the present study, the authors observed regularly an occurrence of a sustaining atrial fibrillation by single injection of carbachol, methacholine or bethanechol into the sinus node artery, and compared with the atrial fibrillation induced by ACh.
収録刊行物
-
- Jpn.J.Pharmacol.
-
Jpn.J.Pharmacol. 21 (2), 167-173, 1971
公益社団法人 日本薬理学会
- Tweet
キーワード
詳細情報 詳細情報について
-
- CRID
- 1390001204289445248
-
- NII論文ID
- 130000837553
-
- NII書誌ID
- AA00691188
-
- COI
- 1:CAS:528:DyaE3MXkslCmtLc%3D
-
- ISSN
- 13473506
- 00215198
-
- NDL書誌ID
- 8509597
-
- PubMed
- 4397202
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可