Studies on .BETA.-pyridylcarbinol as a precursor of nicotinamide adenine dinucleotide.
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- KIZU Akira
- Second Department of Internal Medicine, Kyoto Prefectural University of Medicine
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- NAKAMURA Taizo
- Second Department of Internal Medicine, Kyoto Prefectural University of Medicine
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- KATO Syuji
- Second Department of Internal Medicine, Kyoto Prefectural University of Medicine
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- SAWADA Katsunori
- Second Department of Internal Medicine, Kyoto Prefectural University of Medicine
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- IJICHI Hamao
- Second Department of Internal Medicine, Kyoto Prefectural University of Medicine
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- KURIYAMA Kinya
- Department of Pharmacology, Kyoto Prefectural University of Medicine
Bibliographic Information
- Other Title
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- Studies in β-pyridylcarbinol as a precursor of nicotinamide adenine dinucleotide
- Studies in ベータ pyridylcarbinol as a pre
- EFFECT OF NEUROLEPTIC DRUGS ON THE CONDITIONED BEHAVIOR AFTER PRETREATMENT WITH α-METHYLTYROSINE OR p-CHLOROPHENYLALANINE
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Abstract
The major part of orally administered β-pyridylcarbinol was converted to nicotinic acid in the gastrointestinal tract, whereas that administered intraperitoneally was partially converted to nicotinic acid in the liver. The conversion of this compound to nicotinic acid in both the gastrointestinal tract and liver involved enzymatic processes. The converted nicotinic acid from β-pyridylcarbinol may play a dominant role in the biological actions of β-pyridylcarbinol and possibly involves in the synthesis of NAD via Preiss-Handler's pathway.
Journal
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- The Japanese Journal of Pharmacology
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The Japanese Journal of Pharmacology 27 (6), 817-821, 1977
The Japanese Pharmacological Society
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Keywords
Details 詳細情報について
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- CRID
- 1390001204289570304
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- NII Article ID
- 130000839236
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- NII Book ID
- AA00691188
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- COI
- 1:CAS:528:DyaE1cXotlegsA%3D%3D
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- ISSN
- 13473506
- 00215198
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- NDL BIB ID
- 1916975
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- PubMed
- 204821
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed