Statistical analysis of cutaneous malignant lymphoma in the department of dermatology, Akita university hospital.

DOI 3 References
  • SATO Noriko
    Department of Dermatology, Akita University School of Medicine
  • MAIE Okitaka
    Department of Dermatology, Akita University School of Medicine
  • MASAHASHI Toshiko
    Department of Dermatology, Akita University School of Medicine
  • MURAI Hironobu
    Department of Dermatology, Akita University School of Medicine
  • TADA Yuhei
    Department of Dermatology, Akita University School of Medicine
  • YAGI Eiichi
    Department of Dermatology, Akita University School of Medicine
  • TOMURA Atsuko
    Department of Dermatology, Akita University School of Medicine
  • SATO Toshiki
    Department of Dermatology, Akita University School of Medicine
  • NIIZAWA Midori
    Department of Dermatology, Akita University School of Medicine
  • HAYASAKA Yuko
    Department of Dermatology, Akita University School of Medicine
  • SHIMADA Yumiko
    Department of Dermatology, Akita University School of Medicine
  • TAKAHASHI Shin-ya
    Department of Dermatology, Akita University School of Medicine

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Other Title
  • 秋田大学付属病院皮膚科におけるＣｕｔａｎｅｏｕｓ　Ｍａｌｉｇｎａｎｔ　Ｌｙｍｐｈｏｍａの統計的観察

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A statistical study of 22 cases of cutaneous malignant lymphoma occurring between 1972 and 1988 was carried out on the basis of clinical, histopathological and immunohistochemical findings. The 22 cases comprised of 8 mycosis fungoides, one Sézary syndrome, 4 ATLL, 3B cell lymphomas, 2 true histiocytic lymphomas of the skin and 4 unclassified lymphomas. In accordance with the LSG classifications, the 20 cases, excluding the 2 true histiocytic lymphomas, were classified into three types; namely, 14 cases of diffuse pleomorphic, 4 of diffuse large cell and 2 of diffuse medium sized cell. The 12 cases examined on the lymphocyte subset identification were divided into 9 cases of T cell lymphoma and 3 cases of B cell lymphoma. The median survival period of the patients was estimated at 93 months for mycosis fungoides and Sézary syndrome, 15 months for ATLL, 6 months for B cell lymphoma and 34 months for the others. Autopsy revealed that the tumor cells of mycosis fungoides remained for a long period only in the cutaneous tissue, while those of B cell lymphoma and ATLL invaded into the distant organs a relatively short time after diagnosis was made. In general, the prognosis of all these cases was poor, but 3 patients who received adequate therapy at a very early stage have had satisfactory remissions.

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