A Case of Malignent Melanoma with a Rapid and Complete Spontaneous Regression of Primary Origin.

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  • 短期間で原発巣完全自然消退をみた悪性黒色腫の１例

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Abstract

We report a case of malignant melanoma which showed a spontaneous and complete regression of the primary urigin within a very short period. A 64-year-old woman noticed a subcutaneous tumour in her right inguinal region a month earlier. Although a histological examination of the tumour showed lymph node metastasis of malignant melanoma, an extensive examination of the whole body did not reveal a primary lesion or any other metastasis except for a fingernail sized pigmented freckle on the abdominal site of the right big toe. This pigmented freckle showed an interesting course since it had been unnoticed by the patient until we pointed it out, and it disappeared 2 months later. A histological study of this pigmented freckle revealed the typical findings of a spontaneous regression of the primary lesion of malignant melanoma. A a result, the diagnosis was malignant melanoma, pT0N1M0, stage III. The previous studies have reported malignant melanoma with an unknown primary origin has a relatively good prognosis, but that with a spontaneous and complete regression of primary origin has a poor prognosis.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 61 (4), 467-470, 1999

    Western Division of Japanese Dermatological Association

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