A Case of Erythema Multiforme-type Drug Eruption due to Loflazepate Ethyl (Meilax)

DOI Web Site 3 References
  • ITO Kotaro
    Department of Dermatology, School of Medicine, Fukuoka University
  • KUBOTA Yumiko
    Department of Dermatology, School of Medicine, Fukuoka University
  • YOSHIDA Yuichi
    Department of Dermatology, School of Medicine, Fukuoka University
  • NAKAYAMA Juichiro
    Department of Dermatology, School of Medicine, Fukuoka University

Bibliographic Information

Other Title
  • ロフラゼプ酸エチル（メイラックス）による多形紅斑型薬疹の１例
  • 症例 ロフラゼプ酸エチル(メイラックス)による多形紅斑型薬疹の一例
  • ショウレイ ロフラゼプサン エチル メイラックス ニ ヨル タケイコウ ハンガタヤクシン ノ イチレイ

Search this article

Description

A 43-year-old female had been taking loflazepate ethyl (Meilax®) and sulpiride (Dogmatyl®) for one year and milnacipran (Toledomin®) for 6 months for depressive psychosis. Since these drugs were not very effective, Toledomin® was replaced by maprotiline (Ludiomil®). Two weeks later, at the beginning of October 2004, erythema developed on her dorsal hands. The following day, the erythema spread over her body, and facial edema appeared. She was referred to our hospital. At the first examination, we noted erythema multiforme over her entire body and conjunctival congestion of both eyes with facial edema. Examination of biopsy specimen taken from erythema of the left forearm showed dermal edema and infiltrates of lymphocytes and eosinophils around the vessels in the upper dermis. First, we assigned the diagnosis of drug eruption due to Ludiomil®. After admission, the eruption improved by systemic steroid therapy; however, upon gradual reduction of prednisolone, erythema recurred. The only positive results of the patch test and DLST were for Meilax®. Finally we diagnosed the patient as having drug eruption due to Meilax®, which she had been taking for one year.

Journal

References(3)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top