Clinical Effect of Azelaic Acid on Hyperpigmented Disorders.

  • KAMEYAMA Koichiro
    Department of Dermatology, Kitasato University School of Medicine
  • SAKAI Chie
    Department of Dermatology, Kitasato University School of Medicine
  • KONDO Shigeo
    Department of Dermatology, Kitasato University School of Medicine
  • YONEMOTO KohZoh
    Department of Dermatology, Kitasato University School of Medicine

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Other Title
  • メラニン色素増加疾患に対するアゼライン酸の臨床効果

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Description

The clinical effect of 20% azelaic acid ointment on hyperpigmented disorders such as chloasma, ephelides and reticulate acropigmentation of Kitamura was investigated. Azelaic acid ointment was applied to the patients twice a day, and the clinical effect was evaluated using a color-difference detector. A clinical benefit was observed in 14 out of 20 patients. On the other hand, skin irritation was observed in 2 out of 20 patients. This study shows that azelaic acid ointment can be useful for patients with hyperpigmented disorders.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 55 (2), 319-322, 1993

    Western Division of Japanese Dermatological Association

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