Pathergy Reaction in Sweet's Disease.

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  • 針反応陽性であったＳｗｅｅｔ病の１例

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We report a case of Sweet’s disease which showed a pathergy reaction in a 53-year-old woman. We noted the occurrence of multiple, painful, sharply demarcated, raised erythematous plaques on the face, hands and legs, accompanied by fever, arthralgia and a sore throat. The histology of the plaques on the hands showed neutrophilic infiltration in the dermis, but no leukocytoclastic vasculitis. Cutaneous pathergy, which is well-known to occur in Behçet’s disease or pyoderma gangrenosum, also occurred on the forearm skin which had previously been used for intracutaneus injections. Recent studies have reconfirmed the marked specificity of a positive skin pathergy in Behçet’s disease. This case of Sweet’s disease may have also been complicated with Behçet’s disease. Therefore, when encountering Sweet’s disease, it is important to look for the possibility of a pathergy reaction.

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