A Case of Generalized Argyria

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  • OHMORI Mutsumi
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University
  • URABE Kazunori
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University
  • TSUJITA Jun
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University
  • UCHI Hiroshi
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University
  • KOHDA Futoshi
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University
  • MOROI Yoichi
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University
  • FURUE Masutaka
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University

Bibliographic Information

Other Title
  • 全身の色素沈着を認めた銀皮症の１例
  • 症例 全身の色素沈着を認めた銀皮症の1例
  • ショウレイ ゼンシン ノ シキソ チンチャク オ ミトメタ ギン ヒショウ ノ 1レイ

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Description

A 73-year-old female presented with an 8-month history of blue-gray discoloration of her skin. Discoloration first appeared on the median region of the face, and gradually expanded to the body and palms. Physical examination revealed blue-gray discoloration on her face, chest, upper back, and lateral region of her palms. Histopathological examination showed small black granules scattered in the basal lamina of the eccrine sweat glands and hair follicles. Through careful history taking, she was found to have used a mouthwash containing silver nitrate daily for 3 years for the treatment of oral ulcers. These findings led us to diagnose this case as argyria. The generalized discoloration did not change during the 3-year follow-up period.

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