A Case of Dermatomyositis Associated with Mechanic's Hand

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  • OKAZAKI Shihoko
    Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences
  • OGAWA Fumihide
    Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences
  • YAMAOKA Toshifumi
    Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences
  • SATO Shinichi
    Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences
  • KAJI Kenzo
    Department of Dermatology, Kanazawa University Graduate School of Medical Sciences
  • FUJIMOTO Manabu
    Department of Dermatology, Kanazawa University Graduate School of Medical Sciences
  • KUWANA Masataka
    Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine

Bibliographic Information

Other Title
  • Ｍｅｃｈａｎｉｃ’ｓ　Ｈａｎｄを呈した皮膚筋炎の１例
  • 症例 Mechanic's Handを呈した皮膚筋炎の1例
  • ショウレイ Mechanic s Hand オ テイシタ ヒフ キンエン ノ 1レイ

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Abstract

We report a 49-year old female patient who had dermatomyositis with mechanic's hand. She had erythema on her face and hands 1 month before visiting our hospital. She visited our hospital in February, 2006 and dermatomyositis was diagnosed according to the presence of heliotrope rashes, Gottron's signs, and characteristic erythema with hyperkeratosis (mechanic's hand). Chest computed tomography revealed interstitial pneumonia. Serum creatine phosphokinase levels were within the normal range. Therefore, the patient was given a diagnosis of amyopatic dermatomyositis. Furthermore, we suspected the diagnosis of antisynthetase syndrome by the presence of mechanic's hand and interstitial pneumonia. Daily oral prednisolone of 40 mg in combination with cyclosporine of 125 mg were administered for active interstitial pneumonia. The skin and lung involvement was gradually improved. Immunoprecipitation assay revealed that she had no antisynthetase autoantibody. Thus, it is suggested that the existence of mechanic's hand, which is highly associated with antisynthetase syndrome, dose not always lead to the diagnosis of antisyntetase syndrome.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 70 (6), 606-609, 2008

    Western Division of Japanese Dermatological Association

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