A Case of Atopic Dermatitis with Infective Endocarditis

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  • KAWAHARA Saho
    Division of Dermatology, Kyusyu Central Hospital of the Mutual Aid Association of Public School Teachers
  • MIKUMO Ayako
    Division of Dermatology, Kyusyu Central Hospital of the Mutual Aid Association of Public School Teachers
  • TOYODA Mito
    Division of Dermatology, Kyusyu Central Hospital of the Mutual Aid Association of Public School Teachers
  • KIDO-NAKAHARA Makiko
    Division of Dermatology, Kyusyu Central Hospital of the Mutual Aid Association of Public School Teachers
  • SHIBATA-KIKUCHI Satoko
    Division of Dermatology, Kyusyu Central Hospital of the Mutual Aid Association of Public School Teachers
  • FURUE Masutaka
    Department of Dermatology, Graduate School of Medical Sciences, Kyusyu University

Bibliographic Information

Other Title
  • アトピー性皮膚炎患者に発症した感染性心内膜炎の 1 例
  • 症例 アトピー性皮膚炎患者に発症した感染性心内膜炎の1例
  • ショウレイ アトピーセイ ヒフエン カンジャ ニ ハッショウ シタ カンセンセイシン ナイマクエン ノ 1レイ

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Abstract

A 34-year-old woman with atopic dermatitis was presented to our hospital with fever, visual field defect, purpura and hemorrhagic blisters on both palms and soles. We detected methicillin-sensitive Staphylococcus aureus (MSSA) by culturing blister fluid and circulating blood. Transthoracic echocardiography showed a growth on the mitral valve and mitral regurgitation, indicating a diagnosis of infective endocarditis. As she also suffered a cerebral infarction due to bacterial embolization, surgical intervention was undertaken to cure the infective endocarditis. Only 10 cases of atopic dermatitis with infective endocarditis have been reported in Japan. All of these patients had severe atopic dermatitis with Staphylococcus aureus infection. As Staphylococcus aureus is frequently found colonized on the skin surface of atopic dermatitis patients, it is likely that destruction of the skin barrier may cause sepsis leading to infective endocarditis. In order to avoid these serious complications, it is important to treat the atopic dermatitis appropriately according to standard therapeutic guideline.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 75 (6), 491-495, 2013

    Western Division of Japanese Dermatological Association

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