A Case of Anti-EJ Antibody-Positive Dermatomyositis with Severe Palpebral Edema

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  • IIKAWA Madoka
    Department of Dermatology, School of Medicine, University of Miyazaki
  • Eiji MUROI
    Department of Dermatology, School of Medicine, University of Miyazaki
  • ISHII Yukichika
    Department of Dermatology, School of Medicine, University of Miyazaki
  • MOCHIDA Kousuke
    Department of Dermatology, School of Medicine, University of Miyazaki
  • ODA Yujiro
    Department of Dermatology, School of Medicine, University of Miyazaki
  • SETOYAMA Mitsuru
    Department of Dermatology, School of Medicine, University of Miyazaki
  • NARAHARA Shinichirou
    Narahara Dermatological Clinic
  • HAMAGUCHI Yasuhito
    Department of Dermatology, Kanazawa University Graduate School of Medical Science
  • FUJIMOTO Manabu
    Department of Dermatology, Kanazawa University Graduate School of Medical Science

Bibliographic Information

Other Title
  • 両側眼瞼の著しい腫脹を認めた抗 EJ 抗体陽性皮膚筋炎の 1 例
  • ショウレイ リョウガワ ガンケン ノ イチジルシイ シュチョウ オ ミトメタ コウEJ コウタイ ヨウセイ ヒフ キンエン ノ 1レイ

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Abstract

We report on a 58-year-old female with dermatomyositis. She had noticed bilateral palpebral swelling five years before visiting our hospital. This skin lesion gradually expanded and became very obvious. She also presented with erythema with edema on cheeks, Gottron's sign, and mechanic's hand. Laboratory findings revealed elevations of myogenic enzymes and anti-EJ antibody. An MRI scan revealed a high-intensity region on the thigh muscles. A biopsy specimen from palpebral skin showed interface dermatitis with mucin deposition. Accordingly, we diagnosed her as dermatomyositis. Chest computed tomography and echocardiography revealed interstitial pneumonia and mild pulmonary hypertension. Oral prednisolone improved skin lesions and laboratory data.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 74 (5), 488-492, 2012

    Western Division of Japanese Dermatological Association

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