Two Cases of Angioimmunoblastic T-cell Lymphoma Presenting with a Skin Eruption

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  • KOZONO Kana
    Division of Dermatology, Hiroshima Red Cross Hospital Atomic- bomb Survivors Hospital
  • YAMAMURA Kazuhiko
    Division of Dermatology, Hiroshima Red Cross Hospital Atomic- bomb Survivors Hospital
  • MASHINO Toshihiko
    Division of Dermatology, Hiroshima Red Cross Hospital Atomic- bomb Survivors Hospital
  • FURUE Masutaka
    Department of Dermatology, Kyushu University Graduete School of Medical Sciences
  • ASAOKU Hideki
    Division of Hematology, Hiroshima Red Cross Hospital Atomic-bomb Survivors Hospital
  • FUJIWARA Megumu
    Division of pathology, Hiroshima Red Cross Hospital Atomic-bomb Survivors Hospital

Bibliographic Information

Other Title
  • 皮疹を伴った Angioimmunoblastic T-cell Lymphoma の 2 例
  • ショウレイ ヒシン オ トモナッタ Angioimmunoblastic T-cell Lymphoma ノ 2レイ

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Description

We have experienced two cases of angioimmunoblastic T-cell lymphoma (AITL) presenting with a skin eruption. Patient 1, an 80-year-old woman, had a generalized eruption with faint erythema and some induration. Histopathological examination of the indurated area showed atypical cell infiltration throughout the dermis. Patient 2, a 79-year-old woman, had purpura of the legs. Histopathological examination showed leukocytoclastic vasculitis without atypical cell infiltration. Histopathological examination of the lymph nodes revealed infiltration of atypical lymphocytes and widespread proliferation of the arborizing small vessels, which is a characteristic feature of AITL. About one-half of patients with AITL develop a skin eruption. However, the skin eruption and the histological picture of cutaneous lesions vary considerably. Further accumulation of relevant case studies is required.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 74 (4), 399-404, 2012

    Western Division of Japanese Dermatological Association

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