A Case of Extramammary Paget's Disease with Local Recurrence and Lymph Node Metastasis Following an Interval of 20 Years

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  • MAEKUBO Rie
    Department of Dermatology, Faculty of Medicine, University of Miyazaki
  • MUROI Eiji
    Department of Dermatology, Faculty of Medicine, University of Miyazaki
  • ISHII Yukichika
    Department of Dermatology, Faculty of Medicine, University of Miyazaki
  • MOCHIDA Kosuke
    Department of Dermatology, Faculty of Medicine, University of Miyazaki
  • AMANO Masahiro
    Department of Dermatology, Faculty of Medicine, University of Miyazaki
  • SETOYAMA Mitsuru
    Department of Dermatology, Faculty of Medicine, University of Miyazaki
  • KOBASHI Masahiro
    Kobashi Dermatological Clinic

Bibliographic Information

Other Title
  • 初回治療の20年後に再発，リンパ節転移を生じた乳房外パジェット病の1例
  • 症例 初回治療の20年後に再発,リンパ節転移を生じた乳房外パジェット病の1例
  • ショウレイ ショカイ チリョウ ノ 20ネンゴ ニ サイハツ,リンパセツ テンイ オ ショウジタ チブサ ガイ パジェットビョウ ノ 1レイ

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Abstract

We report on an 89-year-old woman who presented a pruritic erythema on her vulva one year ago. She had been diagnosed as extramammary Paget's disease on her left labium majus, which was excised 20 years ago. We had followed her for five years and confirmed her disease free. A biopsy specimen showed Paget cells located in the epidermis and upper dermis. The diagnosis ofrecurrent extramammary Paget's disease was established. We surgically removed the lesion and carried out sentinel lymph node biopsy. The lymph node specimen showed invasion of Paget cells that were positive stained with CK-7 monoclonal antibody.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 74 (3), 265-268, 2012

    Western Division of Japanese Dermatological Association

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