A Case of Epithelial-myoepithelial Carcinoma Arising in the Submandibular Gland

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  • 顎下腺に発生した上皮筋上皮癌例
  • ガク カセン ニ ハッセイ シタ ジョウヒキン ジョウヒガンレイ

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Abstract

<p>Epithelial-myoepithelial carcinoma (EMC) is a rare malignant salivary gland neoplasm. EMC comprises less than 1% of all salivary gland neoplasms and occurs in the parotid gland in about 80% of cases. Since 1991, 8 cases of EMC of the submandibular gland have been reported. We treated one case of EMC that occurred in the submandibular gland. The patient was a 70-year-old man who had complained of a mass in the right submandibular region for a few years. The mass was removed, together with the right submandibular gland, under general anesthesia. Histologically, the tumor consisted of a proliferation of double-layered duct-like structures with two distinctive cell types. Positron emission tomography (PET) and upper gastrointestinal endoscopy examinations performed during the postoperative period revealed a squamous cell carcinoma of the esophagus with lymph node metastasis. Here, we discuss EMC of the submandibular gland and provide a review of the relevant literature.</p>

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