<i>In Vitro</i> Efficacy of Electrolyzed Dilute Sodium Hypochlorite Solution on<i> Candidal</i> Biofilm

DOI
  • Kashiwabara Toshiya
    Department of Oral and Maxillofacial Prosthodontics, The University of Tokushima, Institute of Health Biosciences
  • Yoneyama Takeyoshi
    Yoneyama Dental Clinic
  • Nakamichi Atsuko
    Faculty of Oral Health, The University of Kobe Tokiwa
  • Honda Tsuyoshi
    Department of Oral and Maxillofacial Prosthodontics, The University of Tokushima, Institute of Health Biosciences
  • Toko Sachie
    Department of Oral and Maxillofacial Prosthodontics, The University of Tokushima, Institute of Health Biosciences
  • Goto Takaharu
    Department of Oral and Maxillofacial Prosthodontics, The University of Tokushima, Institute of Health Biosciences
  • Nagao Kan
    Department of Oral and Maxillofacial Prosthodontics, The University of Tokushima, Institute of Health Biosciences
  • Ichikawa Tetsuo
    Department of Oral and Maxillofacial Prosthodontics, The University of Tokushima, Institute of Health Biosciences

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Other Title
  • <i>In vitro</i> カンジダバイオフィルムに対する電解次亜水の効果

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Description

The effectiveness of oral care interventions for preventing aspiration pneumonia and barriers to compromised elderly is universally-recognized in present medical practice. Quick and effective methods and materials are needed for oral health care. An electrolyzed dilute sodium hypochlorite solution was chosen as a sterilizing solution for oral health care and the sterilizing effect was evaluated using an in vitro candida biofilm. Three electrolyzed functional waters, namely strongly alkaline water, weakly acidic water, dilute sodium hypochlorite solution, two kinds of commercial mouth wash and distilled water were used as test solutions. Antibiofilm efficacy and residual chlorine concentration were evaluated before/after immersing candidal biofilm specimens in each solution. pH changes of the solutions and macroscopic observations of metal surface were evaluated before/after immersing three kinds of dental metals： steel bar, cobalt-chromium alloy and gold-silver-palladium alloy in the solutions to test the corrosion behavior. An electrolyzed dilute sodium hypochlorite solution showed high bactericidal capability of candida biofilm on cell desks and stable concentration of available chlorine, but high induction of metal corrosion.

Journal

  • Ronen Shika Igaku

    Ronen Shika Igaku 28 (3), 277-283, 2014

    Japanese Society of Gerodontology

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