A case of Bowen's disease arising in a region of seborrheic keratosis

DOI 4 References
  • HIDA Tetsuya
    <i>Department of Dermatology, Institute of Health Biosciences, The University of Tokushima Graduate School</i>
  • MATSUDATE Yoshihiro
    <i>Department of Dermatology, Institute of Health Biosciences, The University of Tokushima Graduate School</i>
  • MURAO Kazutoshi
    <i>Department of Dermatology, Institute of Health Biosciences, The University of Tokushima Graduate School</i>
  • KUBO Yoshiaki
    <i>Department of Dermatology, Institute of Health Biosciences, The University of Tokushima Graduate School</i>
  • HIDA Yasutoshi
    <i>Osaki dermatology Clinic</i>

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Other Title
  • 脂漏性角化症病巣内に発生したBowen病の1例

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A 73-year-old Japanese woman was referred to our hospital because of a left leg skin tumor which was gradually growing. Clinical examination revealed a 14 × 13mm brownish keratotic plaque on her leg. Since an excisional biopsy specimen taken by a local dermatologist suggested squamous cell carcinoma, we performed an excisional biopsy. Histologically, the lesion consisted of proliferating keratinocytes. The periphery of the tumor showed reticulated seborrheic keratosis ; whereas in the center portion of the tumor, tumor cells consisted of atypical keratinocytes in the entire epidermis which was considered to be Bowen's disease. We should keep in mind that although rare, skin cancer, including Bowen's disease, could arise in a lesion of seborrheic keratosis.[Skin Cancer (Japan) 2013 ; 28 : 181-184]

Journal

  • Skin Cancer

    Skin Cancer 28 (2), 181-184, 2013

    The Japanese Skin Cancer Society

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