A case of clear cell sarcoma of the foot

DOI 51 References
  • KOMEDANI Azumi
    <i>Department of Plastic and Reconstructive Surgery, Kyoto Medical Center</i>
  • YOSHIOKA Nobutaka
    <i>Department of Plastic and Reconstructive Surgery, Saiseikai Nakatsu Hospital</i>
  • SHINBO Keisuke
    <i>Department of Plastic and Reconstructive Surgery, Kobe University Hospital</i>
  • NAKATANI Hiroko
    <i>Department of Plastic and Reconstructive Surgery, Kurashiki Central Hospital</i>
  • HIRAMOTO Michiaki
    <i>Department of Plastic and Reconstructive Surgery, Saiseikai Nakatsu Hospital</i>

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  • 足部に生じた明細胞肉腫の1例

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Description

We reported a case of clear cell sarcoma of the foot. The patient was a 63-year-old woman who first noticed a small brown nodule on the left medial malleolar region about one year before her first visit to our hospital. She underwent an excisional biopsy by a dermatologist, and the histological diagnosis was clear cell sarcoma. Sentinel lymph node biopsy revealed micrometastases in the inguinal lymph node. Therefore wide local excision and radical inguinal lymph node dissection following DAV-Feron therapy were performed. MRI showed multiple brain metastases five months after surgery and these were successfully treated with γ-knife radiosurgery. She shows no other distant metastasis or local recurrence at 22 months after surgery. Clear cell sarcoma called malignant melanoma of the soft parts is a highly malignant soft tissue tumor. This tumor constitutes less than 1% of all soft tissue malignant sarcomas and has a poor prognosis because of the high incidence of local recurrence and metastases even as a small lesion. Adjuvant chemotherapy and radiotherapy are not confirmed to be effective. Early radical surgery and elective regional lymph node dissection is recommended.[Skin Cancer (Japan) 2010 ; 25 : 94-100]

Journal

  • Skin Cancer

    Skin Cancer 25 (1), 94-100, 2010

    The Japanese Skin Cancer Society

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