The etiological role of HPV in the development of Bowenoid papulosis, and each type of verrucous carcinoma

DOI 65 References
  • EGAWA Kiyofumi
    <i>Department of Dermatology, The Jikei University School of Medicine</i>

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  • Bowen様丘疹症および疣状癌：概念と病態

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Description

Bowenoid papulosis (BP) is a disease characterized by multiple brown-to-black papules on the genitalia, and by histological changes similar to Bowen's disease. Human papillomavirus (HPV) has been reported to induce BP. On the other hand, verrucous carcinoma (VC) is a distinct variant of squamous cell carcinoma (SCC), which is also assumed to be associated with HPV infection. According to the anatomical localization of the tumor, four types can be distinguished : (1) VC of the oral cavity, known as Ackerman carcinoma or oral florid papillomatosis ; (2) VC of the anogenital area, also known as giant condyloma of Buschke-Loewenstein ; (3) VC occurring predominantly on the sole, also known as epithelioma cuniculatum ; and (4) VC occurring in other sites. In this article, the etiological role of HPV is discussed in the development of BP and each type of VC.[Skin Cancer (Japan) 2010 ; 25 : 300-307]

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  • Skin Cancer

    Skin Cancer 25 (3), 300-307, 2010

    The Japanese Skin Cancer Society

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